Psycho-endocrine-immune response to mindfulness-based stress reduction in HIV-infected individuals

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Psycho-endocrine-immune response to mindfulness-based stress reduction in HIV-infected individuals
Stress may hasten HIV disease progression by compromising immune response and increasing viral replication. Conversely, stress reduction may buffer effects of stress on HIV disease. This study determined the effects of an 8-week, mindfulness-based stress reduction (MBSR) program on perceived stress, mood, stress hormones, immune function, and health in HIV infected subjects. A synthesized conceptual framework of psychoneuroimmunology and a transactional model of stress guided the study. A quasi-experimental, repeated-measures, control group design was utilized. Subjects were non-randomly assigned to intervention or control group, and data were collected at baseline, 4 weeks, 8 weeks (immediately post-intervention), and 3 months post-intervention. At 8-weeks the MSBR group showed significant increases (p<0.05;>
